anti-conjugated Uric acid antibodies
Product Number:
AP162
Host:
Rabbit
Clonality:
Polyclonal
Target :
Conjugated Uric acid
Immunogens :
Synthetic Uric acid conjugated to protein carriers (PC)
Quantity :
100µl
Isotype :
IgG
Purity :
previously preabsobed on protein carriers, and ammonium sulphate purified
Form :
Lyophilized
Tested application :
Immunofluorescence. Optimal dilutions should be determined by each laboratory for each application.
Note :
Uric acid is a major endogenous antioxidant and peroxynitrite scavenger.
Storage instructions :
Lyophilized vial must be stored at 4°C in a dry area. After reconstitution with 50μl of distilled water and 50μl of glycerol, the aliquot can be stored at -20°C, and is stable at least 2 years.
Specificity :
Antibody specificity was performed by ELISA competition experiment with the following antigens :
| Compounds | Cross-reactivity ratio (a) |
|---|---|
| Uric acid-GA-PC | 1 |
| Hypoxanthine-GA-PC | 1/> 50,000 |
(a) : Uric acid-GA-PC concentration/other conjugated close-related compounds concentration at half displacement.
GA = Glutaric anhydride
Corresponding antigen :
Gemacbio sells the corresponding antigen : Uric acid (BSA) conjugate (catalog number: AG162)
Reference :
GUERREIRO S., PONCEAU A., TOULORGE D., MARTIN E., ALVAREZ-FISCHER D., HIRSCH E.C. and MICHEL P.P. Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid : potentiation by low-level depolarization. Journal of Neurochemistry (2009) 109, 1118-1128.
For all questions about price and availability of this product, please send us an email specifying your needs. We will immediately send you back a detailed estimate. ab [at] gemacbio [dot] com
