anti-conjugated Malondialdehyde antibodies

Target :

Conjugated Malondialdehyde

Immunogen :

Synthetic Malondialdehyde conjugated to bovine serum albumin (BSA)

Quantity :
100µl
 

Isotype :

IgG

Purity :

Antiserum previously preabsobed on protein carriers, and purified

Form :

Lyophilized

Tested applications :

Immuno-histochemistry, Immunoblot. Optimal dilutions should be determined by each laboratory for each application.

Research areas :

Neuroscience, biochemistry (metabolic ways)

Storage instructions :

Lyophilized vial must be stored at 4°C in a dry area. After reconstitution with 50μl of distilled water and 50μl of glycerol, the aliquot can be stored at -20°C, and is stable at least 2 years.

Specificity :

Using a conjugate Malondialdehyde-Protein, antibody specificity was performed with an ELISA test by competition experiments with the following compounds :

(a) : Malondialdehyde-BSA concentration /conjugated close related structures concentration at half displacement.
BSA = Bovine Serum Albumin.

Corresponding antigen :

Gemacbio sells the corresponding antigen: Malondialdehyde conjugate (code number: AG050)

References :
• MANCUSO M, DAVIDZON G, KURLAN RM, TAWIL R, BONILLA E, DI MAURO S and POWERS JM Hereditary ferritinopathy: a novel mutation, its cellular pathology, and pathogenetic insights. J. Neuropathol. Exp. Neurol. (2005) 64, 280-94.
• ZHOU J, DEO BK, HOSOYA K, TERASAKI T, OBROSOVA IG, BROSIUS FC and KUMAGAI AK Increased JNK Phosphorylation and oxidative stress in response to increased glucose flux through increased GLUT1 expression in rat retinal endothelial cells. Investigative Ophtalmology & Visual Science (2005) 46(9), 3403-10.
• KARUPPAGOUNDER SS, XU H, SHI Q, CHEN LH, PEDRINI S, PECHMAN D, BAKER H, BEAL MF, GANDY SE, GIBSON GE. Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model. Neurobiol Aging (2008)
• FAN LW, MITCHELL HJ, RHODES PG, CAI Z. Alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced neuronal injury in the neonatal rat brain. Neuroscience (2008) 151(3), 737-44.
• NERIA F, CASTILLA MA, SANCHEZ RF, GONZALEZ PACHECO FR, DEUDERO JJ, CALABIA O, TEJEDOR A, MANZARBEITIA F, ORTIZ A, CARAMELO C. Inhibition of JAK2 protects renal endothelial and epithelial cells from oxidative stress and cyclosporin A toxicity. Kidney Int. (2009) 75(2), 227-34.
• REARDON TF and ALLEN DG Iron injections in mice increase skeletal muscle iron content, induce oxidative stress and reduce exercise performance. Exp. Physiol. (2009) 94(6), 720-30.

For all questions about price and availability of this product, please send us an email specifying your needs. We will immediately send you back a detailed estimate. ab [at] gemacbio [dot] com

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